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Diabetes Management for CKD Patients

by Judy Zhu

Chronic kidney disease (CKD) develops when your kidneys become damaged and can't function properly, which includes their ability to filter your blood and eliminate waste. Neglecting this condition could ultimately lead to kidney failure. Thus, it's essential to address health issues related to CKD. This blog aims to introduce several practical methods for managing CKD-related diabetes and potentially preventing further deterioration of kidney function.

CKD is a common occurrence among people with diabetes. Elevated blood sugar levels can harm the blood vessels in the kidneys, causing them to malfunction in blood filtration. Both type 1 and type 2 diabetes can contribute to CKD, but the treatment approaches differ. For individuals with type 1 diabetes, healthcare providers typically prescribe insulin injections, which are the most commonly used treatment method. These injections restore insulin levels in your body, facilitating the removal of excess sugar from your bloodstream. Insulin shots are typically administered using an insulin pen, targeting areas such as the abdomen or upper arm. Insulin plays a crucial role in transporting glucose from the blood into cells, where it serves as an energy source. This action effectively lowers blood sugar levels and prevents hyperglycemia. Proper timing and dosage of insulin injections are vital, so it's important to collaborate closely with your healthcare team to determine the most suitable insulin regimen.

In the context of type 2 diabetes, two common medications for controlling blood sugar are Amaryl and DiaBeta. Amaryl is an oral medication containing an active ingredient called glimepiride. Glimepiride reduces blood sugar levels by stimulating insulin release from pancreatic cells. The peak effect of Amaryl typically occurs 2-3 hours after taking the medication. DiaBeta tablets, on the other hand, contain an active ingredient called glyburide, which also lowers blood sugar levels and promotes increased urination. The use of these medications can vary among individuals, so it's important to follow the guidance of your healthcare provider. Keep in mind that these medications may have side effects, such as nausea, heartburn, dizziness, and stomach discomfort. If you experience any discomfort after taking the medications, don't hesitate to consult with a medical professional.

For managing type 2 diabetes, it's not just about medication. Dietary control and regular exercise are essential components. It's highly recommended to adopt a healthy eating plan that emphasizes good carbohydrates, fiber-rich foods, and healthy fats. Additionally, engaging in moderate physical activity, such as walking, swimming, or cycling, has been shown to effectively regulate blood sugar levels.


  1. Panagiotis Theofilis, Aikaterini Vordoni & Rigas G. Kalaitzidis (2023) Novel therapeutic approaches in the management of chronic kidney disease: a narrative review, Postgraduate Medicine, 135:6, 543-550, DOI: 10.1080/00325481.2023.2233492 

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